A comprehensive description of GluN2B-selective N-methyl-D-aspartate (NMDA) receptor antagonists.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112447
Abstract: l-glutamate is an excitatory neurotransmitter in the central nervous system (CNS), which can activate ionotropic receptors (iGluRs) and metabotropic (mGluRs) receptors. N-methyl-D-aspartate (NMDA) receptor is a ligand-gated ion channel belonging to the iGluRs family. Among… read more here.
Keywords: methyl aspartate; comprehensive description; glun2b; nmda receptor ... See more keywords
A Comprehensive Description of Hypoxia-inducible Factor 2α Inhibitors as Anticancer Agents: A mini-review.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220829095334
Abstract: Targeting the tumor microenvironment is a promising strategy to prevent metastasis, overcome acquired drug resistance, and improve the therapeutic effect. Hypoxia is one of the characteristics of the tumor microenvironment, which is mainly regulated by… read more here.
Keywords: hypoxia inducible; hif; hif hif; tumor ... See more keywords