Articles with "comprehensive mode" as a keyword



Isoniazid and host immune system interactions: A proposal for a novel comprehensive mode of action

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Published in 2019 at "British Journal of Pharmacology"

DOI: 10.1111/bph.14867

Abstract: The known mode of action of isoniazid (INH) is to inhibit bacterial cell wall synthesis following activation by the bacterial catalase–peroxidase enzyme KatG in Mycobacterium tuberculosis (Mtb). This simplistic model fails to explain (a) how… read more here.

Keywords: comprehensive mode; isoniazid; action isoniazid; novel comprehensive ... See more keywords