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   Articles with "comprehensive molecular" as a keyword



Comprehensive molecular profiling of pancreatic ductal adenocarcinoma in FNA, biopsy, and resection specimens

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recommendations! Published in 2022 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22589

Abstract: Molecular testing to identify molecular alterations in pancreatic ductal adenocarcinoma (PDAC) has been increasingly requested because of potential therapeutic implications. In this study, we compared the performance of PDAC fine‐needle aspiration (FNA), fine‐needle biopsy (FNB),… read more here.

Keywords: fna; ductal adenocarcinoma; comprehensive molecular; resection specimens ... See more keywords

Insights into the molecular network characteristics of major HIV-1 subtypes in developed Eastern China: a study based on comprehensive molecular surveillance data

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recommendations! Published in 2024 at "Infection"

DOI: 10.1007/s15010-024-02389-5

Abstract: This study aimed to conduct a comprehensive molecular epidemiology study of major HIV-1 subtypes in developed Eastern China (Zhejiang Province). Plasma samples and epidemiological information were collected from 4180 newly diagnosed HIV-1 positive patients in… read more here.

Keywords: comprehensive molecular; hiv subtypes; hiv; major hiv ... See more keywords

Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.

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recommendations! Published in 2017 at "Cancer cell"

DOI: 10.1016/j.ccell.2017.01.001

Abstract: We report a comprehensive molecular characterization of pheochromocytomas and paragangliomas (PCCs/PGLs), a rare tumor type. Multi-platform integration revealed that PCCs/PGLs are driven by diverse alterations affecting multiple genes and pathways. Pathogenic germline mutations occurred in… read more here.

Keywords: pccs pgls; molecular characterization; characterization pheochromocytoma; comprehensive molecular ... See more keywords
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Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

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recommendations! Published in 2018 at "Cell"

DOI: 10.1016/j.cell.2018.07.036

Abstract: A. Gordon Robertson, Jaegil Kim, Hikmat Al-Ahmadie, Joaquim Bellmunt, Guangwu Guo, Andrew D. Cherniack, Toshinori Hinoue, PeterW. Laird, Katherine A. Hoadley, Rehan Akbani, Mauro A.A. Castro, Ewan A. Gibb, Rupa S. Kanchi, Dmitry A. Gordenin,… read more here.

Keywords: bladder cancer; molecular characterization; invasive bladder; comprehensive molecular ... See more keywords
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Comprehensive molecular scale modeling of anionic surfactant-asphaltene interactions

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recommendations! Published in 2020 at "Fuel"

DOI: 10.1016/j.fuel.2020.119729

Abstract: Abstract Asphaltene is the heaviest fraction of oil sands/bitumen, which is also the leading cause of these oil resources' high viscosity value. Nowadays, steam with additives is used to make oil sands/bitumen mobile through a… read more here.

Keywords: oil sands; comprehensive molecular; molecular scale; molecular interactions ... See more keywords
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Birth of an order: Comprehensive molecular phylogenetic study excludes Herpomyces (Fungi, Laboulbeniomycetes) from Laboulbeniales.

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recommendations! Published in 2019 at "Molecular phylogenetics and evolution"

DOI: 10.1016/j.ympev.2019.01.007

Abstract: The class Laboulbeniomycetes comprises biotrophic parasites associated with arthropods and fungi. Two orders are currently recognized, Pyxidiophorales and Laboulbeniales. Herpomyces is an isolated genus of Laboulbeniales, with species that exclusively parasitize cockroaches (Blattodea). Here, we… read more here.

Keywords: order comprehensive; order; comprehensive molecular; phylogenetic study ... See more keywords
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Comprehensive molecular characterization of mitochondrial genomes in human cancers

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recommendations! Published in 2020 at "Nature Genetics"

DOI: 10.1038/s41588-019-0557-x

Abstract: Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome Consortium/The Cancer Genome Atlas Pan-Cancer Analysis of Whole Genomes Consortium, which aggregated whole-genome sequencing data from… read more here.

Keywords: sequencing data; comprehensive molecular; characterization mitochondrial; mitochondrial genomes ... See more keywords

A Comprehensive Molecular Investigation of α-Thalassemia in an Iranian Cohort from Different Provinces of North Iran

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recommendations! Published in 2017 at "Hemoglobin"

DOI: 10.1080/03630269.2017.1299753

Abstract: Abstract α-Thalassemia (α-thal) is the most common monogenic disease that is caused by the absence or reduced expression of α-globin genes. The aim of this study was to investigate common α-globin mutations and their associated… read more here.

Keywords: molecular investigation; comprehensive molecular; thalassemia; deletion ... See more keywords

Reviewing the occurrence of large genomic rearrangements in patients with inherited cancer predisposing syndromes: importance of a comprehensive molecular diagnosis

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recommendations! Published in 2022 at "Expert Review of Molecular Diagnostics"

DOI: 10.1080/14737159.2022.2049247

Abstract: ABSTRACT Introduction Hereditary cancer predisposition syndromes are caused by germline pathogenic or likely pathogenic variants in cancer predisposition genes (CPG). The majority of pathogenic variants in CPGs are point mutations, but large gene rearrangements (LGRs)… read more here.

Keywords: occurrence large; comprehensive molecular; large genomic; genomic rearrangements ... See more keywords

The comprehensive molecular landscape of the immunologic co-stimulator B7 and TNFR ligand receptor families in colorectal cancer: immunotherapeutic implications with microsatellite instability

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recommendations! Published in 2018 at "Oncoimmunology"

DOI: 10.1080/2162402x.2018.1488566

Abstract: ABSTRACT Immunotherapy is reportedly effective in a subset of colorectal cancers (CRCs) with high microsatellite instability (MSI-H). Exploring the expression patterns and clinical values of immunologic molecules is critical in defining the specific responsive candidates.… read more here.

Keywords: tnfr; comprehensive molecular; microsatellite instability; stimulator tnfr ... See more keywords

MarkerDB 2.0: a comprehensive molecular biomarker database for 2025

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recommendations! Published in 2024 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkae1056

Abstract: Abstract MarkerDB (https://markerdb.ca) has become a leading resource for comprehensive information on molecular biomarkers. Over the past 3 years, the database has evolved significantly, reflecting the dynamic landscape of biomarker research and increasing demands from… read more here.

Keywords: database; comprehensive molecular; markerdb comprehensive; biomarker ... See more keywords