Comprehensive molecular profiling of pancreatic ductal adenocarcinoma in FNA, biopsy, and resection specimens
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22589
Abstract: Molecular testing to identify molecular alterations in pancreatic ductal adenocarcinoma (PDAC) has been increasingly requested because of potential therapeutic implications. In this study, we compared the performance of PDAC fine‐needle aspiration (FNA), fine‐needle biopsy (FNB),… read more here.
Keywords: fna; ductal adenocarcinoma; comprehensive molecular; resection specimens ... See more keywords
Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer cell"
DOI: 10.1016/j.ccell.2017.01.001
Abstract: We report a comprehensive molecular characterization of pheochromocytomas and paragangliomas (PCCs/PGLs), a rare tumor type. Multi-platform integration revealed that PCCs/PGLs are driven by diverse alterations affecting multiple genes and pathways. Pathogenic germline mutations occurred in… read more here.
Keywords: pccs pgls; molecular characterization; characterization pheochromocytoma; comprehensive molecular ... See more keywords
Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.07.036
Abstract: A. Gordon Robertson, Jaegil Kim, Hikmat Al-Ahmadie, Joaquim Bellmunt, Guangwu Guo, Andrew D. Cherniack, Toshinori Hinoue, PeterW. Laird, Katherine A. Hoadley, Rehan Akbani, Mauro A.A. Castro, Ewan A. Gibb, Rupa S. Kanchi, Dmitry A. Gordenin,… read more here.
Keywords: bladder cancer; molecular characterization; invasive bladder; comprehensive molecular ... See more keywords
Comprehensive molecular scale modeling of anionic surfactant-asphaltene interactions
Sign Up to like & getrecommendations! Published in 2020 at "Fuel"
DOI: 10.1016/j.fuel.2020.119729
Abstract: Abstract Asphaltene is the heaviest fraction of oil sands/bitumen, which is also the leading cause of these oil resources' high viscosity value. Nowadays, steam with additives is used to make oil sands/bitumen mobile through a… read more here.
Keywords: oil sands; comprehensive molecular; molecular scale; molecular interactions ... See more keywords
Birth of an order: Comprehensive molecular phylogenetic study excludes Herpomyces (Fungi, Laboulbeniomycetes) from Laboulbeniales.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular phylogenetics and evolution"
DOI: 10.1016/j.ympev.2019.01.007
Abstract: The class Laboulbeniomycetes comprises biotrophic parasites associated with arthropods and fungi. Two orders are currently recognized, Pyxidiophorales and Laboulbeniales. Herpomyces is an isolated genus of Laboulbeniales, with species that exclusively parasitize cockroaches (Blattodea). Here, we… read more here.
Keywords: order comprehensive; order; comprehensive molecular; phylogenetic study ... See more keywords
Comprehensive molecular characterization of mitochondrial genomes in human cancers
Sign Up to like & getrecommendations! Published in 2020 at "Nature Genetics"
DOI: 10.1038/s41588-019-0557-x
Abstract: Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome Consortium/The Cancer Genome Atlas Pan-Cancer Analysis of Whole Genomes Consortium, which aggregated whole-genome sequencing data from… read more here.
Keywords: sequencing data; comprehensive molecular; characterization mitochondrial; mitochondrial genomes ... See more keywords
A Comprehensive Molecular Investigation of α-Thalassemia in an Iranian Cohort from Different Provinces of North Iran
Sign Up to like & getrecommendations! Published in 2017 at "Hemoglobin"
DOI: 10.1080/03630269.2017.1299753
Abstract: Abstract α-Thalassemia (α-thal) is the most common monogenic disease that is caused by the absence or reduced expression of α-globin genes. The aim of this study was to investigate common α-globin mutations and their associated… read more here.
Keywords: molecular investigation; comprehensive molecular; thalassemia; deletion ... See more keywords
Reviewing the occurrence of large genomic rearrangements in patients with inherited cancer predisposing syndromes: importance of a comprehensive molecular diagnosis
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2022.2049247
Abstract: ABSTRACT Introduction Hereditary cancer predisposition syndromes are caused by germline pathogenic or likely pathogenic variants in cancer predisposition genes (CPG). The majority of pathogenic variants in CPGs are point mutations, but large gene rearrangements (LGRs)… read more here.
Keywords: occurrence large; comprehensive molecular; large genomic; genomic rearrangements ... See more keywords
The comprehensive molecular landscape of the immunologic co-stimulator B7 and TNFR ligand receptor families in colorectal cancer: immunotherapeutic implications with microsatellite instability
Sign Up to like & getrecommendations! Published in 2018 at "Oncoimmunology"
DOI: 10.1080/2162402x.2018.1488566
Abstract: ABSTRACT Immunotherapy is reportedly effective in a subset of colorectal cancers (CRCs) with high microsatellite instability (MSI-H). Exploring the expression patterns and clinical values of immunologic molecules is critical in defining the specific responsive candidates.… read more here.
Keywords: tnfr; comprehensive molecular; microsatellite instability; stimulator tnfr ... See more keywords
Comprehensive molecular profiling of the B7 family in gastrointestinal cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cell Proliferation"
DOI: 10.1111/cpr.12468
Abstract: B7 family has been identified as co‐stimulatory or co‐inhibitory molecules on T‐cell response and plays an important role in tumour mortality and malignancy. In this study, the expression pattern of B7 family in gastrointestinal (GI)… read more here.
Keywords: comprehensive molecular; family; molecular profiling; gastrointestinal cancer ... See more keywords
Abstract 4887: Comprehensive molecular analysis of pediatric thalamic tumors
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-4887
Abstract: Childhood thalamic tumors are relatively rare cancers, accounting for 5% of all pediatric brain tumors and categorized as midline gliomas such as diffuse intrinsic pontine gliomas (DIPGs). We and others have shown that mutations in… read more here.
Keywords: gliomas; comprehensive molecular; analysis; molecular analysis ... See more keywords