Diagnostic and therapeutic implications of genetic heterogeneity in myeloid neoplasms uncovered by comprehensive mutational analysis
Sign Up to like & getrecommendations! Published in 2017 at "Leukemia Research Reports"
DOI: 10.1016/j.lrr.2017.09.001
Abstract: While growing use of comprehensive mutational analysis has led to the discovery of innumerable genetic alterations associated with various myeloid neoplasms, the under-recognized phenomenon of genetic heterogeneity within such neoplasms creates a potential for diagnostic… read more here.
Keywords: myeloid neoplasms; genetic heterogeneity; analysis; mutational analysis ... See more keywords
Comprehensive Mutational Analysis of the Lasso Peptide Klebsidin.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00148
Abstract: Antibiotic resistance is a growing threat to public health, making the development of antibiotics of critical importance. One promising class of potential new antibiotics are ribosomally synthesized and post-translationally modified peptides (RiPPs), which include klebsidin,… read more here.
Keywords: lasso peptide; analysis lasso; klebsidin; mutational analysis ... See more keywords