Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention.
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DOI: 10.1016/j.cmet.2019.12.005
Abstract: Type 1 diabetes (T1D) results from the progressive loss of β cells, a process propagated by pro-inflammatory cytokine signaling that disrupts the balance between pro- and anti-apoptotic proteins. To identify proteins involved in this process,… read more here.
Keywords: comprehensive proteomics; human islets; target; proteomics analysis ... See more keywords