3DIV update for 2021: a comprehensive resource of 3D genome and 3D cancer genome
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa1078
Abstract: Abstract Three-dimensional (3D) genome organization is tightly coupled with gene regulation in various biological processes and diseases. In cancer, various types of large-scale genomic rearrangements can disrupt the 3D genome, leading to oncogenic gene expression.… read more here.
Keywords: cancer; comprehensive resource; cancer genome; genome 3div ... See more keywords
CRdb: a comprehensive resource for deciphering chromatin regulators in human
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac960
Abstract: Abstract Chromatin regulators (CRs) regulate epigenetic patterns on a partial or global scale, playing a critical role in affecting multi-target gene expression. As chromatin immunoprecipitation sequencing (ChIP-seq) data associated with CRs are rapidly accumulating, a… read more here.
Keywords: comprehensive resource; crdb; resource; chromatin regulators ... See more keywords
DisCP-Atlas: a comprehensive resource mapping cellular processes to complex diseases.
Sign Up to like & getrecommendations! Published in 2025 at "Nucleic acids research"
DOI: 10.1093/nar/gkaf1129
Abstract: Abstract Genome-wide association studies (GWAS) have identified thousands of disease-associated loci, yet translating these findings into biological mechanisms remains challenging. Single–cell RNA–sequencing provides functional annotation at cellular resolution. Most current resources connect disease associations only… read more here.
Keywords: cellular processes; discp atlas; atlas comprehensive; comprehensive resource ... See more keywords
ASTRA: a comprehensive resource of stress-induced transcriptional activity in human cell lines.
Sign Up to like & getrecommendations! Published in 2025 at "Nucleic acids research"
DOI: 10.1093/nar/gkaf1174
Abstract: Abstract The atlas of stress response activity (ASTRA) is an open-access, curated database cataloging transcriptomic responses to stress in human cell lines, organized by major stress categories to advance research on conserved and stress-specific pathways,… read more here.
Keywords: cell lines; human cell; stress; cell ... See more keywords
PCsRNAdb: a comprehensive resource of small noncoding RNAs across cancers.
Sign Up to like & getrecommendations! Published in 2025 at "Nucleic acids research"
DOI: 10.1093/nar/gkaf992
Abstract: Abstract Small noncoding RNAs (sncRNAs) constitute a diverse class of endogenous transcripts, including miRNAs, piRNAs, tRNA-derived fragments (tDRs), rRNA-derived fragments (rRFs), and other small RNAs. They have been identified as pivotal regulatory elements in a… read more here.
Keywords: cancers pcsrnadb; pcsrnadb comprehensive; analysis; noncoding rnas ... See more keywords
TCMID 2.0: a comprehensive resource for TCM
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx1028
Abstract: Abstract As a traditional medical intervention in Asia and a complementary and alternative medicine in western countries, Traditional Chinese Medicine (TCM) is capturing worldwide attention in life science field. Traditional Chinese Medicine Integrated Database (TCMID),… read more here.
Keywords: medicine; resource tcm; tcmid comprehensive; comprehensive resource ... See more keywords
CORUM: the comprehensive resource of mammalian protein complexes—2019
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky973
Abstract: Abstract CORUM is a database that provides a manually curated repository of experimentally characterized protein complexes from mammalian organisms, mainly human (67%), mouse (15%) and rat (10%). Given the vital functions of these macromolecular machines,… read more here.
Keywords: protein; comprehensive resource; mammalian protein; corum comprehensive ... See more keywords