Efficient synthesis of a novel series of indeno-fused pyrido[2,3-d]pyrimidines using a deep eutectic solvent system comprised of choline chloride/urea
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DOI: 10.3184/175815517x14981249895596
Abstract: A series of 13 aryl indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidine-2,4,6-(3H,5H,11H)-triones, eight of which are new, were synthesised regioselectively in high yields by a three-component reaction of 1,3-indanedione, an araldehyde and 6-aminopyrimidin-2,4(1H,3H)-dione in the presence of a deep eutectic solvent… read more here.
Keywords: choline chloride; comprised choline; series; deep eutectic ... See more keywords