Memantine treatment does not affect compulsive behavior or frontostriatal connectivity in an adolescent rat model for quinpirole-induced compulsive checking behavior.
Sign Up to like & getrecommendations! Published in 2022 at "Psychopharmacology"
DOI: 10.1007/s00213-022-06139-z
Abstract: RATIONALE Compulsivity often develops during childhood and is associated with elevated glutamate levels within the frontostriatal system. This suggests that anti-glutamatergic drugs, like memantine, may be an effective treatment. OBJECTIVE Our goal was to characterize… read more here.
Keywords: memantine treatment; compulsive checking; treatment; memantine ... See more keywords
When it's at: An examination of when cognitive change occurs during cognitive therapy for compulsive checking in obsessive-compulsive disorder.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of behavior therapy and experimental psychiatry"
DOI: 10.1016/j.jbtep.2018.12.003
Abstract: BACKGROUND AND OBJECTIVES The cognitive theory of compulsive checking in OCD proposes that checking behaviour is maintained by maladaptive beliefs, including those related to inflated responsibility and those related to reduced memory confidence. This study… read more here.
Keywords: responsibility; cognitive therapy; compulsive checking; memory confidence ... See more keywords
Visuospatial working memory capacity moderates the relationship between anxiety and OCD related checking behaviors
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.1039849
Abstract: Background Compulsive checking behavior is the most prevalent compulsive behavior in patients with obsessive-compulsive disorder (OCD). While some studies have shown that anxiety and executive function influence compulsive checking behavior, the relationship between these constructs… read more here.
Keywords: working memory; compulsive checking; visuospatial working; anxiety ... See more keywords