Behavioral and neural mechanisms underlying habitual and compulsive drug seeking
Sign Up to like & getrecommendations! Published in 2018 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2017.09.003
Abstract: ABSTRACT Addiction is characterized by compulsive drug use despite negative consequences. Here we review studies that indicate that compulsive drug use, and in particular punishment resistance in animal models of addiction, is related to impaired… read more here.
Keywords: control; drug use; drug; compulsive drug ... See more keywords
Compulsive drug-taking is associated with habenula-frontal cortex connectivity.
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2208867119
Abstract: Significance The habenula is a relay node between the forebrain and midbrain regions and plays an essential role in making decisions based on the value of choices. Compulsive drug use, as the defining feature of… read more here.
Keywords: habenula frontal; compulsive drug; drug taking; drug ... See more keywords