Chronic voluntary caffeine intake in male Wistar rats reveals individual differences in addiction-like behavior
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2020.172880
Abstract: Caffeine is the most widely consumed psychoactive substance in the world. However, there is controversy about whether becoming addicted to caffeine is possible and a lack of well-established animal models to examine caffeine consumption. The… read more here.
Keywords: caffeine; caffeine consumption; like behavior; compulsive like ... See more keywords
Insula to ventral striatal projections mediate compulsive eating produced by intermittent access to palatable food
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-019-0538-x
Abstract: Compulsive eating characterizes many binge-related eating disorders, yet its neurobiological basis is poorly understood. The insular cortex subserves visceral-emotional functions, including taste processing, and is implicated in drug craving and relapse. Here, via optoinhibition, we… read more here.
Keywords: insula ventral; intermittent access; access palatable; compulsive eating ... See more keywords
Intermittent Access to Ethanol Drinking Facilitates the Transition to Excessive Drinking After Chronic Intermittent Ethanol Vapor Exposure
Sign Up to like & getrecommendations! Published in 2017 at "Alcoholism: Clinical and Experimental Research"
DOI: 10.1111/acer.13434
Abstract: BACKGROUND Alcohol binge drinking in humans is thought to increase the risk for alcohol use disorder (AUD). Unclear is whether drinking patterns (e.g., bingelike or stable drinking) differentially affect the transition to compulsive-like drinking in… read more here.
Keywords: drinking; transition; cie; compulsive like ... See more keywords
Compulsive‐like eating of high‐fat high‐sugar food is associated with ‘addiction‐like’ glutamatergic dysfunction in obesity prone rats
Sign Up to like & getrecommendations! Published in 2022 at "Addiction Biology"
DOI: 10.1111/adb.13206
Abstract: Chronic overeating is a core feature of diet‐induced obesity. There is increasing evidence that in vulnerable individuals, such overeating could become compulsive, resembling an addictive disorder. The transition to compulsive substance use has been linked… read more here.
Keywords: addiction like; diet induced; compulsive like; addiction ... See more keywords
Behavioral restriction, lorazepam, and escitalopram uniquely influence the expression of naturalistic stereotypy in deer mice: perspectives on anxiety- and compulsive-like behavior
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2022.1071157
Abstract: Introduction: Stereotypical expression in laboratory-housed rodents can be explained by different motivational, coping, and motor dysfunction theories. Here, we aimed to explore the neurocognitive underpinnings of high stereotypical (HS) expression in deer mice (Peromyscus maniculatus… read more here.
Keywords: expression; compulsive like; behavioral restriction; deer mice ... See more keywords
Bidirectional Behavioral Selection in Mice: A Novel Pre-clinical Approach to Examining Compulsivity
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2021.716619
Abstract: Obsessive-compulsive disorder (OCD) and related disorders (OCRD) is one of the most prevalent neuropsychiatric disorders with no definitive etiology. The pathophysiological attributes of OCD are driven by a multitude of factors that involve polygenic mechanisms,… read more here.
Keywords: mice novel; novel pre; bidirectional behavioral; compulsive like ... See more keywords