Computation‐Guided Design of a Stimulus‐Responsive Multienzyme Supramolecular Assembly
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201700425
Abstract: The construction of stimulus-responsive supramolecular complexes of metabolic pathway enzymes, inspired by natural multienzyme assemblies (metabolons), provides an attractive avenue for efficient and spatiotemporally controllable one-pot biotransformations. We have constructed a phosphorylation- and optically responsive… read more here.
Keywords: stimulus; guided design; computation guided; multienzyme ... See more keywords
Computation-guided asymmetric total syntheses of resveratrol dimers
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-021-27546-4
Abstract: Although computational simulation-based natural product syntheses are in their initial stages of development, this concept can potentially become an indispensable resource in the field of organic synthesis. Herein we report the asymmetric total syntheses of… read more here.
Keywords: total syntheses; resveratrol dimers; computational simulation; asymmetric total ... See more keywords