Computational analysis of neurodevelopmental phenotypes: Harmonization empowers clinical discovery
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24389
Abstract: Making a specific diagnosis in neurodevelopmental disorders is traditionally based on recognizing clinical features of a distinct syndrome, which guides testing of its possible genetic etiologies. Scalable frameworks for genomic diagnostics, however, have struggled to… read more here.
Keywords: analysis neurodevelopmental; phenotypes harmonization; computational analysis; harmonization empowers ... See more keywords
Steric and Electronic Effects in Gold N‐Heterocyclic Carbene Complexes Revealed by Computational Analysis
Sign Up to like & getrecommendations! Published in 2019 at "ChemistryOpen"
DOI: 10.1002/open.201900076
Abstract: Abstract A computational analysis of a series of cationic and neutral gold imidazolylidene and benzimidizolylidene complexes is reported. The Bond Dissociation Energies of the various ligands in the complexes calculated at the PBE0‐D3/def2‐TZVP level of… read more here.
Keywords: effects gold; steric electronic; analysis; computational analysis ... See more keywords
Computational Analysis of Protein Tunnels and Channels.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7366-8_3
Abstract: Protein tunnels connecting the functional buried cavities with bulk solvent and protein channels, enabling the transport through biological membranes, represent the structural features that govern the exchange rates of ligands, ions, and water solvent. Tunnels… read more here.
Keywords: protein; protein tunnels; tunnels channels; computational analysis ... See more keywords
Computational Analysis of Altering Cell Fate.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9224-9_17
Abstract: The notion of reprogramming cell fate is a direct challenge to the traditional view in developmental biology that a cell's phenotypic identity is sealed after undergoing differentiation. Direct experimental evidence, beginning with the somatic cell… read more here.
Keywords: computational analysis; analysis altering; cell fate; biology ... See more keywords
Variations in Healthy Swallowing Mechanics During Various Bolus Conditions Using Computational Analysis of Swallowing Mechanics (CASM)
Sign Up to like & getrecommendations! Published in 2019 at "Dysphagia"
DOI: 10.1007/s00455-019-10026-9
Abstract: Bolus properties such as volume, consistency, and density have been shown to influence swallowing through the analysis of kinematics and timing in both normal and disordered swallowing. However, inherent intra- and inter-person variability of swallowing… read more here.
Keywords: bolus conditions; group; computational analysis; swallowing mechanics ... See more keywords
Computational Analysis of Artimisinin Derivatives on the Antitumor Activities
Sign Up to like & getrecommendations! Published in 2017 at "Natural Products and Bioprospecting"
DOI: 10.1007/s13659-017-0142-x
Abstract: The study on antitumor activities of artemisinin and its derivatives has been closely focused on in recent years. Herein, 2D and 3D QSAR analysis was performed on the basis of a series of artemisinin derivatives… read more here.
Keywords: artimisinin derivatives; antitumor activities; analysis; computational analysis ... See more keywords
Computational Analysis of Strouhal Number Variation in Vortex Meters
Sign Up to like & getrecommendations! Published in 2019 at "Journal of The Institution of Engineers (India): Series C"
DOI: 10.1007/s40032-019-00509-x
Abstract: Vortex meters are used to measure the flow rate by measuring the vortex shedding frequency behind a trapezoidal (or triangular)-shaped body. In the current work, analysis of various parameters affecting the performance of vortex flowmeters… read more here.
Keywords: variation; strouhal number; vortex meters; computational analysis ... See more keywords
Computational Analysis of the Mechanism of the Ubiquitin Conjugating Enzyme Ubc13
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1579
Abstract: case we examined the sodiumdependent glucose co-transporter of Vibrio parahaemolyticus (vSGLT) which mediates galactose transport into the cytoplasm of vibrio parahaemolyticus bacteria. According literature, kinetic of cotransporter has between 5 and 6 states or conformations,… read more here.
Keywords: analysis mechanism; conjugating enzyme; analysis; computational analysis ... See more keywords
Computational analysis of energy and cost efficient retrofitting measures for the French house
Sign Up to like & getrecommendations! Published in 2020 at "Building and Environment"
DOI: 10.1016/j.buildenv.2020.106792
Abstract: Abstract Energy-efficient housing has become a mandatory aim to address climate change. This paper presents a computational analysis taking a French single family house as a case study, and aims to investigate both energy and… read more here.
Keywords: energy cost; energy; cost; computational analysis ... See more keywords
Multi-scale computational analysis of unidirectional carbon fiber reinforced polymer composites under various loading conditions
Sign Up to like & getrecommendations! Published in 2018 at "Composite Structures"
DOI: 10.1016/j.compstruct.2018.05.025
Abstract: Abstract A multi-scale computational analysis based on representative volume element (RVE) modeling and molecular dynamics (MD) simulations is developed to investigate the microscopic failure mechanisms of unidirectional (UD) carbon fiber reinforced polymer (CFRP) composites. The… read more here.
Keywords: carbon fiber; unidirectional carbon; scale computational; computational analysis ... See more keywords
Parametric computational analysis for punching shear in RC slabs
Sign Up to like & getrecommendations! Published in 2018 at "Engineering Structures"
DOI: 10.1016/j.engstruct.2018.03.035
Abstract: Abstract One of the key phenomena in flat slab structures is their punching shear behaviour. The real importance of punching shear consists of a sudden brittle fracture, which can trigger catastrophic consequences for humans. This… read more here.
Keywords: parametric computational; punching shear; computational analysis; model ... See more keywords