Modeling aging and its impact on cellular function and organismal behavior
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2021.111577
Abstract: Aging is a complex phenomenon of functional decay in a biological organism. Although the effects of aging are readily recognizable in a wide range of organisms, the cause(s) of aging are ill defined and poorly… read more here.
Keywords: aging impact; modeling aging; biology; computational biology ... See more keywords
Quantum annealing versus classical machine learning applied to a simplified computational biology problem
Sign Up to like & getrecommendations! Published in 2018 at "npj Quantum Information"
DOI: 10.1038/s41534-018-0060-8
Abstract: Transcription factors regulate gene expression, but how these proteins recognize and specifically bind to their DNA targets is still debated. Machine learning models are effective means to reveal interaction mechanisms. Here we studied the ability… read more here.
Keywords: machine; machine learning; quantum annealing; biology ... See more keywords
Characterizing domain-specific open educational resources by linking ISCB Communities of Special Interest to Wikipedia
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac236
Abstract: Abstract Motivation Wikipedia is one of the most important channels for the public communication of science and is frequently accessed as an educational resource in computational biology. Joint efforts between the International Society for Computational… read more here.
Keywords: special interest; communities special; iscb communities; wikipedia ... See more keywords
Scalable Data Mining Algorithms in Computational Biology and Biomedicine
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/5652041
Abstract: 1School of Computer Science and Technology, Tianjin University, Tianjin 300354, China 2Institute of Informatics, Silesian University of Technology, 44-100 Gliwice, Poland 3Department of Mathematics and Statistics and Department of Agronomy, Horticulture, and Plant Science, BioSNTR,… read more here.
Keywords: data mining; mining algorithms; scalable data; biology ... See more keywords
A practical guide to methods controlling false discoveries in computational biology
Sign Up to like & getrecommendations! Published in 2019 at "Genome Biology"
DOI: 10.1186/s13059-019-1716-1
Abstract: BackgroundIn high-throughput studies, hundreds to millions of hypotheses are typically tested. Statistical methods that control the false discovery rate (FDR) have emerged as popular and powerful tools for error rate control. While classic FDR methods… read more here.
Keywords: false discoveries; biology; computational biology; fdr methods ... See more keywords
PLoS Computational Biology Issue Image | Vol. 17(9) October 2021.
Sign Up to like & getrecommendations! Published in 2021 at "PLoS computational biology"
DOI: 10.1371/image.pcbi.v17.i09
Abstract: The tomato flowers are characterized by possessing poricidal anthers, which restrict the exit of the pollen to a tiny opening on the apex of the anther. To extract pollen efficiently, some visiting bees grasp the… read more here.
Keywords: biology issue; image; plos computational; biology ... See more keywords
A field guide to cultivating computational biology
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001419
Abstract: Evolving in sync with the computation revolution over the past 30 years, computational biology has emerged as a mature scientific field. While the field has made major contributions toward improving scientific knowledge and human health,… read more here.
Keywords: biology field; guide cultivating; biology; computational biology ... See more keywords
Wisdom of crowds in computational biology
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1007032
Abstract: Scientific advances are frequently catalyzed by exploring the intersection of disciplines. From its inception, PLOS Computational Biology has published key insights that advance our understanding of biology and medicine—advances enabled by developments in computation and… read more here.
Keywords: medicine; machine learning; plos computational; biology ... See more keywords
Ten simple rules for typographically appealing scientific texts
Sign Up to like & getrecommendations! Published in 2020 at "PLoS computational biology"
DOI: 10.1371/journal.pcbi.1008458
Abstract: Text is ubiquitous in everyday scientific work—when was the last time you spent 5 minutes working without writing, reading, or interacting with any kind of equipment that had text (scales, labels, brand name, etc.) on… read more here.
Keywords: text; computational biology; biology; ten simple ... See more keywords
Advancing computational biology and bioinformatics research through open innovation competitions
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0222165
Abstract: Open data science and algorithm development competitions offer a unique avenue for rapid discovery of better computational strategies. We highlight three examples in computational biology and bioinformatics research in which the use of competitions has… read more here.
Keywords: research; advancing computational; biology; bioinformatics research ... See more keywords
Bruins-in-Genomics: Evaluation of the impact of a UCLA undergraduate summer program in computational biology on participating students
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0268861
Abstract: Recruiting, training and retaining scientists in computational biology is necessary to develop a workforce that can lead the quantitative biology revolution. Yet, African-American/Black, Hispanic/Latinx, Native Americans, and women are severely underrepresented in computational biosciences. We… read more here.
Keywords: program; summer program; computational biology; bruins genomics ... See more keywords