A Combined Computational Methodology for the Discovery of Hit Compounds with Putative Insect Repellency Properties
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DOI: 10.1002/cmdc.202200271
Abstract: Mosquitoes and other hematophagous arthropods, the primary vectors of multiple parasites and viruses, are responsible for the transmission of serious diseases to humans. Nowadays, the interest is focused on the development of novel repellents to… read more here.
Keywords: methodology; methodology discovery; hit compounds; computational methodology ... See more keywords
A Computational Methodology to Overcome the Challenges Associated With the Search for Specific Enzyme Targets to Develop Drugs Against Leishmania major
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DOI: 10.1177/1177932217712471
Abstract: We present an approach for detecting enzymes that are specific of Leishmania major compared with Homo sapiens and provide targets that may assist research in drug development. This approach is based on traditional techniques of… read more here.
Keywords: methodology; leishmania major; search; computational methodology ... See more keywords