Computational Opportunities and Challenges in Finding Cyclic Peptide Modulators of Protein-Protein Interactions.
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DOI: 10.1007/978-1-4939-9504-2_5
Abstract: Peptide cyclization can improve stability, conformational constraint, and compactness. However, apart from beta-turn structures, which are well incorporated into cyclic peptides (CPs), many primary peptide structures and functions are markedly altered by cyclization. Accordingly, to… read more here.
Keywords: peptide; cyclic peptide; opportunities challenges; computational opportunities ... See more keywords