Computational redesign of penicillin acylase for cephradine synthesis with high kinetic selectivity
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DOI: 10.1039/c8gc03420f
Abstract: Computational redesign of native enzyme active sites for non-natural substrates offers a general approach for creating biocatalysts in green chemistry. Herein, a computational strategy was developed to discover selective mutants of penicillin acylase to catalyze… read more here.
Keywords: penicillin acylase; chemistry; cephradine; computational redesign ... See more keywords