Computational systems approach towards phosphoproteomics and their downstream regulation
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202200068
Abstract: Protein phosphorylation plays an essential role in modulating cell signalling and its downstream transcriptional and translational regulations. Until recently, protein phosphorylation has been studied mostly using low‐throughput biochemical assays. The advancement of mass spectrometry (MS)‐based… read more here.
Keywords: approach towards; systems approach; phosphoproteomics downstream; computational systems ... See more keywords
Computational systems biology of cellular processes in Arabidopsis thaliana: an overview
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03379-9
Abstract: Systems biology strives for gaining an understanding of biological phenomena by studying the interactions of different parts of a system and integrating the knowledge obtained into the current view of the underlying processes. This is… read more here.
Keywords: plant; arabidopsis thaliana; computational systems; biology ... See more keywords
A Computational Systems Approach to Rational Design of Nose-to-Brain Delivery of Biopharmaceutics
Sign Up to like & getrecommendations! Published in 2019 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.9b04885
Abstract: In this work, a computational systems approach, comprising models at different time and length scales, is developed to elucidate the fundamental chemical, physical, transport, and biological proces... read more here.
Keywords: nose brain; approach rational; design nose; rational design ... See more keywords
Application of conditional robust calibration to ordinary differential equations models in computational systems biology: a comparison of two sampling strategies.
Sign Up to like & getrecommendations! Published in 2020 at "IET systems biology"
DOI: 10.1049/iet-syb.2018.5091
Abstract: Mathematical modelling is a widely used technique for describing the temporal behaviour of biological systems. One of the most challenging topics in computational systems biology is the calibration of non-linear models; i.e. the estimation of… read more here.
Keywords: robust calibration; computational systems; biology; systems biology ... See more keywords
Intersectional Experiences of Unfair Treatment Caused by Automated Computational Systems
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the ACM on Human-Computer Interaction"
DOI: 10.1145/3555546
Abstract: This paper reports on empirical work conducted to study perceptions of unfair treatment caused by automated computational systems. While the pervasiveness of algorithmic bias has been widely acknowledged, and perceptions of fairness are commonly studied… read more here.
Keywords: computational systems; caused automated; automated computational; unfair treatment ... See more keywords
Editorial: Integrative Computational Systems Biology Approaches in Immunology and Medicine
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DOI: 10.3389/fmicb.2018.03338
Abstract: Editorial on the Research Topic "Integrative Computational Systems Biology Approaches in Immunology and Medicine" read more here.
Keywords: integrative computational; medicine; computational systems; biology ... See more keywords
A Computational Systems Pharmacology Approach to Investigate Molecular Mechanisms of Herbal Formula Tian-Ma-Gou-Teng-Yin for Treatment of Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00668
Abstract: Traditional Chinese medicine (TCM) is typically prescribed as formula to treat certain symptoms. A TCM formula contains hundreds of chemical components, which makes it complicated to elucidate the molecular mechanisms of TCM. Here, we proposed… read more here.
Keywords: formula; systems pharmacology; computational systems; pharmacology ... See more keywords
Situatedness and Embodiment of Computational Systems
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DOI: 10.3390/e19040162
Abstract: In this paper, the role of the environment and physical embodiment of computational systems for explanatory purposes will be analyzed. In particular, the focus will be on cognitive computational systems, understood in terms of mechanisms… read more here.
Keywords: simon; situatedness embodiment; embodiment computational; view ... See more keywords