Inhibition of catechol-O-methyltransferase in the cynomolgus monkey by opicapone after acute and repeated administration
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DOI: 10.1016/j.neuropharm.2018.10.001
Abstract: Introduction: The aim of the study was to clarify the dose response for inhibition of catechol‐O‐methyltransferase (COMT) by opicapone, a third generation COMT inhibitor, after acute and repeated administration to the cynomolgus monkey with pharmacokinetic… read more here.
Keywords: opicapone; inhibition; comt inhibition; repeated administration ... See more keywords