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   Articles with "comt val158met" as a keyword



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Appetite effects of prefrontal stimulation depend on COMT Val158Met polymorphism: A randomized clinical trial

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recommendations! Published in 2019 at "Appetite"

DOI: 10.1016/j.appet.2019.05.015

Abstract: The regulation of appetite is supported by dopamine-modulated brain circuits. Recent studies have shown that transcranial direct current stimulation (tDCS) aimed at increasing the excitability of the dorsolateral prefrontal cortex can reduce appetite, but the… read more here.

Keywords: stimulation; comt val158met; val158met polymorphism; tdcs ... See more keywords
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The divergent impact of catechol-O-methyltransferase (COMT) Val158Met genetic polymorphisms on executive function in adolescents with discrete patterns of childhood adversity.

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recommendations! Published in 2018 at "Comprehensive psychiatry"

DOI: 10.1016/j.comppsych.2017.11.004

Abstract: PURPOSE Catechol-O-methyltransferase (COMT) Val158Met functional polymorphisms play a crucial role in the development of executive function (EF), but their effect may be moderated by environmental factors such as childhood adversity. The present study aimed at… read more here.

Keywords: childhood; childhood adversity; function; comt val158met ... See more keywords

Motor learning and COMT Val158met polymorphism: Analyses of oculomotor behavior and corticocortical communication

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recommendations! Published in 2020 at "Neurobiology of Learning and Memory"

DOI: 10.1016/j.nlm.2020.107157

Abstract: Differences in motor learning can be partially explained by differences in genotype. The catechol-O-methyltransferase (COMT) Val158Met polymorphism regulates the dopamine (DA) availability in the prefrontal cortex modulating motor learning and performance. Given the differences in… read more here.

Keywords: comt val158met; val158met polymorphism; motor learning; motor ... See more keywords

Interaction between childhood adversity and functional polymorphisms in the dopamine pathway on first-episode psychosis

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recommendations! Published in 2019 at "Schizophrenia Research"

DOI: 10.1016/j.schres.2018.04.010

Abstract: BACKGROUND There is consistent evidence of a cumulative relationship between childhood adversity and psychosis, with number of adversities experienced increasing the probability of psychosis onset. It is possible that genetic factors moderate the association between… read more here.

Keywords: val158met akt1; childhood; comt val158met; childhood adversity ... See more keywords
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Task demands, tDCS intensity, and the COMT val158met polymorphism impact tDCS-linked working memory training gains

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-14030-7

Abstract: Working memory (WM) training paired with transcranial direct current stimulation (tDCS) can improve executive function in older adults. The unclear mechanism of tDCS likely depends on tDCS intensity, and task relevant genetic factors (e.g., for… read more here.

Keywords: tdcs; comt val158met; training; working memory ... See more keywords

Interrogating the Relationship Between Schizotypy, the Catechol-O-Methyltransferase (COMT) Val158Met Polymorphism, and Neuronal Oscillatory Activity.

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recommendations! Published in 2018 at "Cerebral cortex"

DOI: 10.1093/cercor/bhy171

Abstract: The COMT Val158Met polymorphism affects the availability of synaptic dopamine in the prefrontal cortex and has been widely studied as a genetic risk factor for psychosis. Schizotypy is associated with an increased risk of psychosis,… read more here.

Keywords: schizotypy; comt val158met; val158met polymorphism; comt ... See more keywords

Association of Catechol-O-methyltransferase (COMT Val158Met) with future risk of cardiovascular disease in depressed individuals - a Swedish population-based cohort study

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recommendations! Published in 2018 at "BMC Medical Genetics"

DOI: 10.1186/s12881-018-0645-2

Abstract: BackgroundCatechol-O-methyltransferase (COMT Val158Met) has been implicated in both depression and cardiovascular disease. The purpose of this study was to assess if COMT Val158Met, which influences the COMT enzyme activity, has an effect on the risk… read more here.

Keywords: depression; risk; comt val158met; comt ... See more keywords
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COMT Val158Met Polymorphism Influences the Cerebral Blood Flow Changes Related to Psychomotor Retardation in Major Depressive Disorder

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recommendations! Published in 2022 at "Neuropsychiatric Disease and Treatment"

DOI: 10.2147/ndt.s379146

Abstract: Background Previous studies revealed different cerebral blood flow (CBF) changes of major depressive disorder (MDD) patients with psychomotor retardation (PMR). These different changes might result from the modulation of other factors, such as genes. This… read more here.

Keywords: cbf; comt; psychomotor retardation; comt val158met ... See more keywords

COMT Val158Met Polymorphism and Social Impairment Interactively Affect Attention-Deficit Hyperactivity Symptoms in Healthy Adolescents

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recommendations! Published in 2018 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2018.00284

Abstract: The dopaminergic system has been shown to have substantial effects on the etiology of attention-deficit hyperactivity disorder (ADHD). However, while some studies found a significant direct effect, others did not. In this context, social behavior… read more here.

Keywords: symptomatology; deficit hyperactivity; comt val158met; impairment ... See more keywords

The inconsistent mediating effect of catechol O methyl transferase Val158Met polymorphism on the sex difference of cognitive impairment in schizophrenia patients

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recommendations! Published in 2022 at "Frontiers in Psychiatry"

DOI: 10.3389/fpsyt.2022.993859

Abstract: Objective Schizophrenia is a multifaceted mental disorder characterized by heterogeneous positive/negative symptoms and cognitive deficits. Sex differences have been reported in various aspects of the disease. However, the underlying genetic reasons remain unelucidated. Recent studies… read more here.

Keywords: polymorphism; val158met rs4680; comt val158met; sex ... See more keywords