Splenectomy Promotes Macrophage Polarization in a Mouse Model of Concanavalin A- (ConA-) Induced Liver Fibrosis
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DOI: 10.1155/2019/5756189
Abstract: Background Splenectomy can improve liver function and survival in patients with autoimmune hepatitis (AIH) and liver cirrhosis. We investigated the underlying mechanism in a mouse model of concanavalin A- (ConA-) induced liver fibrosis. Methods We… read more here.
Keywords: splenectomy; liver fibrosis; cona; mouse model ... See more keywords
IgE, IgG1, and IgG4 Reactivity to Dermatophagoides pteronyssinus Glycosylated Extract in Allergic Patients
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DOI: 10.1155/2019/9840890
Abstract: Background House dust mites are important allergen sources and some of these allergenic proteins may contain carbohydrate moieties, which are able to be isolated using lectins, as Concanavalin A (ConA). This study aimed to investigate… read more here.
Keywords: cona unbound; ige igg1; cona; cona bound ... See more keywords
NOD-Like Receptor Protein 3 Inflammasome-Dependent IL-1β Accelerated ConA-Induced Hepatitis
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DOI: 10.3389/fimmu.2018.00758
Abstract: Autoimmune hepatitis (AIH) is a progressive inflammatory disorders of unknown etiology, characterized by immune-mediated destruction of hepatocytes and massive production of cytokines. Interleukin-1β is a pleiotropic proinflammatory cytokine and well known to be critical in… read more here.
Keywords: cona induced; hepatitis; inflammasome dependent; cona ... See more keywords
CP-25 exerts a protective effect against ConA-induced hepatitis via regulating inflammation and immune response
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1041671
Abstract: Hepatitis is a complex multifactorial pathological disorder, which can eventually lead to liver failure and even potentially be life threatening. Paeoniflorin-6′-O-benzene sulfonate (CP-25) has proven to have critical anti-inflammatory effects in arthritis. However, the effects… read more here.
Keywords: inflammation; exerts protective; hepatitis; induced hepatitis ... See more keywords