Toward Compilation of Balanced Protein Stability Data Sets: Flattening the ΔΔG Curve through Systematic Enrichment
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DOI: 10.1021/acs.jcim.2c00054
Abstract: Often studies analyzing stability data sets and/or predictors ignore neutral mutations and use a binary classification scheme labeling only destabilizing and stabilizing mutations. Recognizing that highly concentrated neutral mutations interfere with data set quality, we… read more here.
Keywords: protein stability; concentrated neutral; stability data; neutral mutations ... See more keywords