Agonist efficiency from concentration-response curves: structural implications and applications.
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DOI: 10.1016/j.bpj.2021.02.034
Abstract: Agonists are evaluated by a concentration-response curve (CRC), with a midpoint (EC50) that indicates potency, a high-concentration asymptote that indicates efficacy and a low-concentration asymptote that indicates constitutive activity. A third agonist attribute, efficiency (η),… read more here.
Keywords: concentration response; agonist efficiency; concentration asymptote; concentration ... See more keywords