Articles with "concentrations endogenous" as a keyword



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Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers.

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Published in 2019 at "Drug metabolism and pharmacokinetics"

DOI: 10.1016/j.dmpk.2018.09.003

Abstract: This study aimed to elucidate the impact of OATP1B1 genotype (*1b/*1b, *1b/*15, and *15/*15) on plasma concentrations of endogenous OATP1B1 substrates. Healthy volunteers with OATP1B1 *1b/*1b (n = 10), *1b/*15 (n = 7), or *15/*15 (n = 2) received oral administration… read more here.

Keywords: plasma concentrations; concentrations endogenous; healthy volunteers; endogenous oatp1b1 ... See more keywords