Pharmacokinetics and Comprehensive Analysis of the Tissue Distribution of Eravacycline in Rabbits
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DOI: 10.1128/aac.00275-18
Abstract: Eravacycline (7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline or TP-434) is a novel, fully synthetic broad-spectrum fluorocycline with potent activity against Gram-positive bacteria, anaerobes, and multidrug-resistant Enterobacteriaceae. We characterized the plasma pharmacokinetics of eravacycline and conducted a comprehensive analysis of the… read more here.
Keywords: tissue distribution; analysis; comprehensive analysis; concentrations highest ... See more keywords