Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau
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DOI: 10.1016/j.neurobiolaging.2019.03.015
Abstract: Chronic kynurenine pathway (KP) activation is implicated in Alzheimer's disease (AD) pathophysiology and results in quinolinic acid-induced excitotoxic stimulation of the N-methyl-D-aspartate receptor. However, most studies focus on plasma and it is unclear if peripheral… read more here.
Keywords: tau; alzheimer disease; csf; kynurenine pathway ... See more keywords