Phenylbutazone blood and urine concentrations, pharmacokinetics, and effects on biomarkers of inflammation in horses following intravenous and oral administration of clinical doses.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2553
Abstract: Phenylbutazone (PBZ) is a potent mon-steroidal anti-inflammatory drug used commonly in performance horses. The objectives of the current study were to describe blood and urine concentrations and the pharmacokinetics of PBZ and its metabolites following… read more here.
Keywords: administration; urine concentrations; blood urine; concentrations pharmacokinetics ... See more keywords
Concentrations, pharmacokinetics and selected pharmacodynamics of morphine and its active metabolites following oral administration to horses.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.13122
Abstract: The metabolism and pharmacokinetics of intravenous (i.v.) morphine in the horse have been described; however, administration of therapeutic doses has also been associated with neuroexcitation and adverse gastrointestinal effects. In this study, we hypothesized that… read more here.
Keywords: administration; concentrations pharmacokinetics; following oral; pharmacokinetics selected ... See more keywords