Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency
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DOI: 10.1038/s41598-017-02927-2
Abstract: Arginase-1 deficiency in humans is a rare genetic disorder of metabolism resulting from a loss of arginase-1, leading to impaired ureagenesis, hyperargininemia and neurological deficits. Previously, we generated a tamoxifen-inducible arginase-1 deficient mouse model harboring… read more here.
Keywords: concept gene; arginase; proof concept; inducible arginase ... See more keywords