Plants as a cost‐effective source for customizable photosynthetic wound dressings: A proof of concept study
Sign Up to like & getrecommendations! Published in 2024 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28705
Abstract: Oxygen is essential for tissue regeneration, playing a crucial role in several processes, including cell metabolism and immune response. Therefore, the delivery of oxygen to wounds is an active field of research, and recent studies… read more here.
Keywords: tissue regeneration; concept study; oxygen; proof concept ... See more keywords
Using ex vivo bioengineered lungs to model pathologies and screening therapeutics: A proof‐of‐concept study
Sign Up to like & getrecommendations! Published in 2024 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28754
Abstract: Respiratory diseases, claim over eight million lives annually. However, the transition from preclinical to clinical phases in research studies is often hindered, partly due to inadequate representation of preclinical models in clinical trials. To address… read more here.
Keywords: pathologies screening; proof concept; using vivo; model ... See more keywords
A Machine Learning Approach for Handling Big Data Produced by High Resolution Mass Spectrometry after Data Independent Acquisition of Small Molecules - Proof of Concept Study Using an Artificial Neural Network for Sample Classification.
Sign Up to like & getrecommendations! Published in 2020 at "Drug testing and analysis"
DOI: 10.1002/dta.2775
Abstract: Liquid chromatography coupled to high-resolution mass spectrometry (HRMS) enables data independent acquisition (DIA) and untargeted screening. However, to avoid the handling of the resulting large dataset, most laboratories in that field still use targeted screening… read more here.
Keywords: machine; high resolution; machine learning; proof concept ... See more keywords
Nitrates in combination with hydralazine in cardiorenal syndrome: a randomized controlled proof‐of‐concept study
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13076
Abstract: Cardiorenal syndrome (CRS) is a common problem of great morbidity and mortality. Hydralazine–isosorbide dinitrate (H‐ISDN) may be used in renal failure and may improve exercise capacity in heart failure (HF). Our proof‐of‐concept study aimed to… read more here.
Keywords: proof concept; cardiorenal syndrome; concept study;
Efficacy of Semaglutide as Adjuvant Treatment for Sleeve Gastrectomy: A Proof‐of‐Concept Study in Mice
Sign Up to like & getrecommendations! Published in 2025 at "Obesity"
DOI: 10.1002/oby.70003
Abstract: This proof‐of‐concept study evaluated the impact of adding semaglutide as an adjuvant therapy to sleeve gastrectomy (SG) on weight loss and metabolic outcomes in obese mice. read more here.
Keywords: sleeve gastrectomy; semaglutide adjuvant; concept study; proof concept ... See more keywords
Paradoxical home temperatures during cold weather: a proof-of-concept study
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Biometeorology"
DOI: 10.1007/s00484-020-01998-7
Abstract: There is substantial epidemiological evidence on the associations between cold weather and adverse health effects. Meteorological alarm systems are being developed globally, and generalized protective advice is given to the public based on outdoor exposure… read more here.
Keywords: proof concept; concept study; cold weather; controlled apartments ... See more keywords
Wearable haptic anklets for gait and freezing improvement in Parkinson’s disease: a proof-of-concept study
Sign Up to like & getrecommendations! Published in 2020 at "Neurological Sciences"
DOI: 10.1007/s10072-020-04485-4
Abstract: Background and objective In a proof-of-concept study, we aimed to verify whether the wearable haptic anklets, a device that delivers personalized suprathreshold alternating exteroceptive stimulation at the anklets on demand, may improve the quality of… read more here.
Keywords: wearable haptic; haptic anklets; proof concept; concept study ... See more keywords
Vibro-tactile stimulation of the neck reduces pain in people with cervical dystonia: a proof-of-concept study
Sign Up to like & getrecommendations! Published in 2024 at "Neurological Sciences"
DOI: 10.1007/s10072-024-07561-1
Abstract: Pain is a common non-motor symptom in patients with cervical dystonia (CD), severely impacting their quality of life. The pathophysiology of CD is incompletely understood but it involves altered processing of proprioceptive and pain signals.… read more here.
Keywords: proof concept; pain; stimulation; concept study ... See more keywords
Proof-of-Concept Study of the NOTI Chelating Platform: Preclinical Evaluation of 64Cu-Labeled Mono- and Trimeric c(RGDfK) Conjugates
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-020-01530-8
Abstract: Purpose We recently developed a chelating platform based on the macrocycle 1,4,7-triazacyclononane with up to three five-membered azaheterocyclic arms for the preparation of 68 Ga- and 64 Cu-based radiopharmaceuticals. Based on this platform, the chelator… read more here.
Keywords: chelating platform; noti tva; rgdfk; proof concept ... See more keywords
Good gamers, good managers? A proof-of-concept study with Sid Meier’s Civilization
Sign Up to like & getrecommendations! Published in 2020 at "Review of Managerial Science"
DOI: 10.1007/s11846-020-00378-0
Abstract: Human resource professionals increasingly enhance their assessment tools with game elements—a process typically referred to as “gamification”—to make them more interesting and engaging for candidates, and they design and use “serious games” that can support… read more here.
Keywords: game; proof concept; civilization; concept study ... See more keywords
Biopartitioning micellar electrokinetic chromatography – Concept study of cationic analytes
Sign Up to like & getrecommendations! Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2019.104518
Abstract: Abstract In the early stages of drug discovery, beyond the biological activity screening, the physicochemical properties including lipophilicity, ionization, solubility as well as metabolic profiling and protein-binding affinity should be determined for each drug candidate.… read more here.
Keywords: chromatography; electrokinetic chromatography; chromatography concept; concept study ... See more keywords