Embryo‐maternal dialogue during pregnancy establishment and implantation in the pig
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.22835
Abstract: Porcine conceptuses secrete pregnancy‐recognition signals (estrogens, including estradiol‐17β) that inhibit luteolysis, thereby prolonging progesterone production by corpora lutea. The supportive mechanism by which the conceptus also inhibits luteolysis is by shifting endometrial prostaglandin (PG) synthesis… read more here.
Keywords: pregnancy; conceptus; implantation; embryo maternal ... See more keywords
Expression of glucose transporters in the endometrium and early conceptus membranes of the horse.
Sign Up to like & getrecommendations! Published in 2018 at "Placenta"
DOI: 10.1016/j.placenta.2018.06.308
Abstract: INTRODUCTION Glucose is the primary energy substrate for early conceptus development and, for the first 40 days of gestation, the equine conceptus depends solely on glucose available in the histotroph; thereafter, histotrophic glucose provision continues… read more here.
Keywords: conceptus membranes; glucose transporters; conceptus; expression ... See more keywords
Maternal recognition of pregnancy and implantation are not associated with an interferon response of the endometrium to the presence of the conceptus in dromedary camel.
Sign Up to like & getrecommendations! Published in 2017 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2016.11.033
Abstract: Maternal recognition of pregnancy (MRP) and implantation involve appropriate interactions between the elongating conceptus and the receptive endometrium that will condition development of the feto-placental unit to term. Molecular mechanisms that take place at the… read more here.
Keywords: pregnancy; dromedary camel; conceptus; endometrium ... See more keywords
Extracellular vesicle mediated intercellular communication at the porcine maternal-fetal interface: A new paradigm for conceptus-endometrial cross-talk
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40476
Abstract: Exosomes and microvesicles are extracellular vesicles released from cells and can contain lipids, miRNAs and proteins that affect cells at distant sites. Recently, microvesicles containing miRNA have been implicated in uterine microenvironment of pigs, a… read more here.
Keywords: cross talk; endometrial cross; conceptus; maternal fetal ... See more keywords
Conceptus interferon gamma is essential for establishment of pregnancy in the pig.
Sign Up to like & getrecommendations! Published in 2021 at "Biology of reproduction"
DOI: 10.1093/biolre/ioab186
Abstract: Establishment and maintenance of pregnancy in the pig is a complex process that relies on conceptus regulation of the maternal proinflammatory response to endometrial attachment. Following elongation, pig conceptuses secrete interferon gamma (IFNG) during attachment… read more here.
Keywords: pregnancy; conceptus; interferon gamma; ifng ... See more keywords
Calcium-binding proteins S100A8, S100A9, and S100A12: expression and regulation at the maternal-conceptus Interface in pigs†.
Sign Up to like & getrecommendations! Published in 2022 at "Biology of reproduction"
DOI: 10.1093/biolre/ioac039
Abstract: Among the many calcium-binding proteins, S100A8, S100A9, and S100A12 play important roles in inflammation, innate immunity, and antimicrobial function, but their expression, regulation, and function at the maternal-conceptus interface in pigs are not fully understood.… read more here.
Keywords: s100a8 s100a9; conceptus; expression; s100a9 s100a12 ... See more keywords
Pig conceptuses utilize extracellular vesicles for interferon-gamma-mediated paracrine communication with the endometrium
Sign Up to like & getrecommendations! Published in 2024 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioae044
Abstract: Abstract Interferon-gamma (IFNG) is a pro-inflammatory cytokine secreted by the porcine conceptus (embryo and extra-embryonic membranes) during the peri-implantation period of pregnancy. IFNG modifies the endometrial inflammatory immune response and is required for the implantation… read more here.
Keywords: extracellular vesicles; interferon gamma; conceptus; biology ... See more keywords
Evidence for metabolism of creatine by the conceptus, placenta, and uterus for production of adenosine triphosphate during conceptus development in pigs
Sign Up to like & getrecommendations! Published in 2024 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioae088
Abstract: Abstract In pigs, the majority of embryonic mortality occurs when free-floating conceptuses (embryos/fetuses and associated placental membranes) elongate, and the uterine–placental interface undergoes folding and develops areolae. Both periods involve proliferation, migration, and changes in… read more here.
Keywords: conceptus; conceptus development; adenosine triphosphate; creatine ... See more keywords
A bovine 3D endometrium-on-a-chip reveals the role of conceptus-derived proteins, CAPG and PDI, in conceptus–endometrial communication
Sign Up to like & getrecommendations! Published in 2025 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioaf077
Abstract: Abstract Early embryo loss affects all mammalian species, including humans, and agriculturally important food-producing mammals such as cattle. The developing conceptus (embryo and extraembryonic membranes) secretes proteins that can modify the endometrium and can be… read more here.
Keywords: capg pdi; conceptus; culture; endometrium ... See more keywords
Uterine epithelial expression of the tumor necrosis factor superfamily: a strategy for immune privilege during pregnancy in a true epitheliochorial placentation species
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz233
Abstract: Abstract The maternal immune system tolerates semi-allogeneic placental tissues during pregnancy. Fas ligand (FASLG) and tumor necrosis factor superfamily 10 (TNFSF10) are known to be components of maternal immune tolerance in humans and mice. However,… read more here.
Keywords: immune privilege; pregnancy; conceptus; tnfsf10 ... See more keywords
Form of dietary selenium affects mRNA encoding interferon-stimulated and progesterone-induced genes in the bovine endometrium and conceptus length at maternal recognition of pregnancy.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of animal science"
DOI: 10.1093/jas/skac137
Abstract: Widespread regions of the southeast United States have soils, and hence forages, deficient in selenium (Se), necessitating Se supplementation to grazing cattle for optimal immune function, growth, and fertility. We have reported that supplementation with… read more here.
Keywords: conceptus; recognition pregnancy; development; mix ... See more keywords