Concise, stereocontrolled and modular syntheses of the anti-influenza rubrolides R and S
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DOI: 10.1016/j.tetlet.2019.151307
Abstract: Abstract The fungal metabolites rubrolide R and S were synthesized in concise, entirely stereoselective fashion through the combined use of bromine-stereodirected vinylogous aldol condensation (SVAC) and Suzuki cross-coupling. A bioinspired, high-yield conversion of rubrolide R… read more here.
Keywords: concise stereocontrolled; influenza rubrolides; anti influenza; modular syntheses ... See more keywords
Concise Stereocontrolled Synthesis of an α-Carbagalactose Segment of RCAI-56, a Candidate Anticancer Agent
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DOI: 10.1055/s-0037-1611806
Abstract: RCAI-56 is a synthetic glycolipid exhibiting a potent antitumor activity by stimulation of natural killer T cells. Tetra-O-benzyl-α-carbagalactose, an important synthetic segment of RCAI-56, was stereoselectively synthesized from 1,4-dichloro-2-butene in nine steps, including the key… read more here.
Keywords: stereocontrolled synthesis; rcai; concise stereocontrolled; segment rcai ... See more keywords