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Concomitant KRAS and BRAF mutations in colorectal cancer.

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1 Published in 2019 at "Journal of gastrointestinal oncology"

DOI: 10.21037/jgo.2019.01.10

Abstract: BRAF and KRAS are two key oncogenes in the RAS/RAF/MEK/MAP-kinase signaling pathway. While previously considered mutually exclusive, concomitant mutations in both KRAS and BRAF genes have been identified in colorectal cancer (CRC). The clinical outcome… read more here.

Keywords: colorectal cancer; concomitant kras; kras braf; braf mutations ... See more keywords