Abstract LB-249: Examination of analytical factors impacting concordance of plasma-tumor testing by next-generation sequencing (NGS)
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DOI: 10.1158/1538-7445.am2017-lb-249
Abstract: The increased usage of circulating tumor DNA (ctDNA) sequencing for oncology clinical research demonstrates a critical need for sensitive and specific testing. While we have observed a high degree of concordance between single tumor mutations… read more here.
Keywords: concordance plasma; concordance; examination analytical; plasma tumor ... See more keywords
Abstract 1379: Insights into analytical factors impacting variant concordance of plasma-tumor NGS testing
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DOI: 10.1158/1538-7445.sabcs18-1379
Abstract: Next generation sequencing (NGS) of circulating free DNA (cfDNA) is transforming the treatment paradigm in oncology. Sensitive non-invasive cfDNA assays could revolutionize clinical trial design with improved patient safety. However, there are substantial challenges to… read more here.
Keywords: early stage; tumor; stage; oncology ... See more keywords