Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome
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DOI: 10.1016/j.cell.2018.10.057
Abstract: Phase transitions involving biomolecular liquids are a fundamental mechanism underlying intracellular organization. In the cell nucleus, liquid-liquid phase separation of intrinsically disordered proteins (IDPs) is implicated in assembly of the nucleolus, as well as transcriptional… read more here.
Keywords: liquid nuclear; condensates mechanically; sense restructure; restructure genome ... See more keywords