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Published in 2019 at "Chemical Science"
DOI: 10.1039/c8sc03530j
Abstract: The condensation domain synthesising the last peptide bond in glycopeptide antibiotic biosynthesis has a preference for linear peptide substrates, with effective peptide formation linked to the rate of amino acid activation by the preceding adenylation…
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Keywords:
antibiotic biosynthesis;
condensation domain;
glycopeptide antibiotic;