Common Fragile Sites Are Characterized by Faulty Condensin Loading after Replication Stress
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DOI: 10.1016/j.celrep.2020.108177
Abstract: Summary Cells coordinate interphase-to-mitosis transition, but recurrent cytogenetic lesions appear at common fragile sites (CFSs), termed CFS expression, in a tissue-specific manner after replication stress, marking regions of instability in cancer. Despite such a distinct… read more here.
Keywords: common fragile; replication; replication stress; condensin loading ... See more keywords