Condition-specific mortality risk can explain differences in COVID-19 case fatality ratios around the globe
Sign Up to like & getrecommendations! Published in 2020 at "Public Health"
DOI: 10.1016/j.puhe.2020.08.021
Abstract: Objectives With COVID-19 infections resulting in death according to a hierarchy of risks, with age and pre-existing health conditions enhancing disease severity, the objective of this study is to estimate the condition-specific Case Fatality Ratio… read more here.
Keywords: mortality risk; pre existing; condition specific; mortality ... See more keywords
A two-stream convolutional neural network for microRNA transcription start site feature integration and identification
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-85173-x
Abstract: MicroRNAs (miRNAs) play important roles in post-transcriptional gene regulation and phenotype development. Understanding the regulation of miRNA genes is critical to understand gene regulation. One of the challenges to study miRNA gene regulation is the… read more here.
Keywords: condition specific; mirna; mirna tss; specific mirna ... See more keywords
Condition-specific 3' mRNA isoform half-lives and stability elements in yeast.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2301117120
Abstract: Alternative polyadenylation generates numerous 3' mRNA isoforms that can differ in their stability, structure, and function. These isoforms can be used to map mRNA stabilizing and destabilizing elements within 3' untranslated regions (3'UTRs). Here, we… read more here.
Keywords: condition specific; mrna isoform; condition; stability elements ... See more keywords
TF-Prioritizer: a Java pipeline to prioritize condition-specific transcription factors
Sign Up to like & getrecommendations! Published in 2022 at "GigaScience"
DOI: 10.1101/2022.10.19.512881
Abstract: Background Eukaryotic gene expression is controlled by cis-regulatory elements (CREs), including promoters and enhancers, which are bound by transcription factors (TFs). Differential expression of TFs and their binding affinity at putative CREs determine tissue- and… read more here.
Keywords: seq; condition specific; activity; transcription factors ... See more keywords
Conditional Convolution Projecting Latent Vectors on Condition-Specific Space.
Sign Up to like & getrecommendations! Published in 2022 at "IEEE transactions on neural networks and learning systems"
DOI: 10.1109/tnnls.2022.3172512
Abstract: Despite rapid advancements over the past several years, the conditional generative adversarial networks (cGANs) are still far from being perfect. Although one of the major concerns of the cGANs is how to provide the conditional… read more here.
Keywords: conditional convolution; condition specific; layer; generator ... See more keywords
Genome-Wide Analysis of Yeast Metabolic Cycle through Metabolic Network Models Reveals Superiority of Integrated ATAC-seq Data over RNA-seq Data
Sign Up to like & getrecommendations! Published in 2022 at "mSystems"
DOI: 10.1128/msystems.01347-21
Abstract: Dynamic chromatin organization mediates the emergence of condition-specific phenotypes in eukaryotic organisms. Saccharomyces cerevisiae can alter its metabolic profile via regulation of genome accessibility and robust transcriptional oscillations under nutrient-limited conditions. Thus, both epigenetic information… read more here.
Keywords: information; seq data; metabolic cycle; condition specific ... See more keywords