Conditional expression of Ki-RasG12V in the mammary epithelium of transgenic mice induces estrogen receptor alpha (ERα)-positive adenocarcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Oncogene"
DOI: 10.1038/onc.2017.252
Abstract: Appropriate ‘in vivo’ models are crucial for studying breast cancer biology and evaluating the efficacy of therapeutic agents. Thus we engineered a novel transgenic mouse line expressing the human Ki-Ras bearing an activating mutation (Ki-Ras(G12V))… read more here.
Keywords: mammary epithelium; conditional expression; transgenic mice; breast cancer ... See more keywords
Partial masculinization of Aedes aegypti females by conditional expression of Nix
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010598
Abstract: Background Aedes aegypti, the main vector of dengue, yellow fever, and other arboviruses thrives in tropical and subtropical areas around the globe putting half of the world’s population at risk. Despite aggressive efforts to control… read more here.
Keywords: aedes aegypti; expression nix; control; expression ... See more keywords