Conditional power and predictive power based on right censored data with supplementary auxiliary information.
Sign Up to like & getrecommendations! Published in 2018 at "Statistics in medicine"
DOI: 10.1002/sim.7673
Abstract: Conditional power and predictive power provide estimates of the probability of success at the end of the trial based on the information from the interim analysis. The observed value of the time to event endpoint… read more here.
Keywords: information; conditional power; predictive power; power ... See more keywords
Statistical inference following sample size adjustment based on the 50%-conditional-power principle
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biopharmaceutical Statistics"
DOI: 10.1080/10543406.2017.1372766
Abstract: ABSTRACT Sample size adjustment at an interim analysis can mitigate the risk of failing to meet the study objective due to lower-than-expected treatment effect. Without modification to the conventional statistical methods, the type I error… read more here.
Keywords: conditional power; size adjustment; size; sample size ... See more keywords
Estimation of conditional power for cluster-randomized trials with interval-censored endpoints.
Sign Up to like & getrecommendations! Published in 2020 at "Biometrics"
DOI: 10.1111/biom.13360
Abstract: Cluster-randomized trials (CRTs) of infectious disease preventions often yield correlated, interval-censored data: dependencies may exist between observations from the same cluster, and event occurrence may be assessed only at intermittent study visits. This data structure… read more here.
Keywords: conditional power; interval censored; cluster randomized; cluster ... See more keywords
INTERIM ANALYSIS OF CLINICAL TRIALS: SIMULATION STUDIES OF CONDITIONAL POWER UNDER FRACTIONAL BROWNIAN MOTION
Sign Up to like & getrecommendations! Published in 2019 at "Fractals"
DOI: 10.1142/s0218348x19501330
Abstract: Classical Brownian motion (BM) techniques for statistical monitoring of clinical trials have been widely used. The conditional power (CP) and α-spending function-based boundary crossing probabiliti... read more here.
Keywords: conditional power; brownian motion; interim analysis; clinical trials ... See more keywords
Conditional power of antidepressant network meta-analysis
Sign Up to like & getrecommendations! Published in 2021 at "BMC Psychiatry"
DOI: 10.1186/s12888-021-03094-5
Abstract: Background Conditional power of network meta-analysis (NMA) can support the planning of randomized controlled trials (RCTs) assessing medical interventions. Conditional power is the probability that updating existing inconclusive evidence in NMA with additional trial(s) will… read more here.
Keywords: network; conditional power; analysis; evidence ... See more keywords