Articles with "conditional single" as a keyword



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Conditional Single Vector CRISPR/SaCas9 Viruses for Efficient Mutagenesis in the Adult Mouse Nervous System

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Published in 2020 at "Cell reports"

DOI: 10.1016/j.celrep.2020.02.092

Abstract: SUMMARY Mice engineered for conditional, cell type-specific gene inactivation have dominated the field of mouse genetics because of the high efficiency of Cre-loxP-mediated recombination. Recent advances in CRISPR/Cas9 technologies have provided alternatives for rapid gene… read more here.

Keywords: single vector; mutagenesis; vector; sacas9 ... See more keywords