The selective FKBP51 inhibitor SAFit2 reduces alcohol consumption and reinstatement of conditioned alcohol effects in mice
Sign Up to like & getrecommendations! Published in 2019 at "Addiction Biology"
DOI: 10.1111/adb.12758
Abstract: There is still no widely effective pharmacotherapy for alcohol addiction available in the clinic. FK506‐binding protein 51 (FKBP51) is a negative regulator of the glucocorticoid receptor signaling pathway that regulates the stress‐induced glucocorticoid feedback circuit.… read more here.
Keywords: safit2; alcohol consumption; conditioned alcohol; alcohol effects ... See more keywords