Conditioned pain modulation affects the N2/P2 complex but not the N1 wave: A pilot study with laser‐evoked potentials
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Pain"
DOI: 10.1002/ejp.1693
Abstract: The ‘pain‐inhibits‐pain’ effect stems from neurophysiological mechanisms involving endogenous modulatory systems termed diffuse noxious inhibitory controls (DNIC) or conditioned pain modulation (CPM). Laser‐evoked potentials (LEPs) components, the N2/P2 complex, and the N1 wave, reflect the… read more here.
Keywords: pain modulation; complex wave; laser evoked; conditioned pain ... See more keywords
Conditioned pain modulation—A comprehensive review
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DOI: 10.1016/j.neucli.2020.11.002
Abstract: Conditioned pain modulation (CPM) is a centrally processed measure of the net effect of the descending pain pathway. This comprises both the facilitatory as well as the inhibitory effect. In the past, CPM or similar… read more here.
Keywords: pain modulation; cpm; conditioned pain; modulation comprehensive ... See more keywords
Conditioned pain modulation in patients with nonspecific chronic back pain with chronic local pain, chronic widespread pain, and fibromyalgia
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DOI: 10.1097/j.pain.0000000000000777
Abstract: Abstract Findings considering conditioned pain modulation (CPM) in chronic back pain (CBP) are contradictory. This might be because many patients with CBP report pain in further areas of the body, and altered CPM might influence… read more here.
Keywords: back pain; pain modulation; cpm; cwp ... See more keywords
Individual differences in conditioned pain modulation are associated with functional connectivity within the descending antinociceptive pathway
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DOI: 10.1097/j.pain.0000000000003478
Abstract: Supplemental Digital Content is Available in the Text. Individuals who exhibit inhibitory conditioned pain modulation, but not those with no or faciliatory conditioned pain modulation, have resting-state functional connectivity of their descending antinociceptive pathway. read more here.
Keywords: pain modulation; antinociceptive pathway; descending antinociceptive; conditioned pain ... See more keywords
Acute postoperative pain after orthognathic surgery can be predicted by the preoperative evaluation of conditioned pain modulation and pain catastrophizing
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DOI: 10.1097/pr9.0000000000000989
Abstract: Presurgical conditioned pain modulation and pain catastrophizing scale assessments can be used to predict acute postoperative pain in patients undergoing orthognathic surgery. Abstract Introduction: The incidence and severity of chronic postoperative pain (POP) are major… read more here.
Keywords: pain; conditioned pain; cpm; orthognathic surgery ... See more keywords
Impaired conditioned pain modulation was restored after a single exercise session in individuals with and without fibromyalgia
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DOI: 10.1097/pr9.0000000000000996
Abstract: Supplemental Digital Content is Available in the Text. Submaximal isometric exercise improved impaired conditioned pain modulation acutely in individuals with and without fibromyalgia, regardless of health status. Abstract Introduction: Exercise is an effective nonpharmacological intervention… read more here.
Keywords: exercise; conditioned pain; pain; session ... See more keywords
Sex differences in conditioned pain modulation effects and its associations with autonomic nervous system activities in healthy, younger individuals: a pilot study
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DOI: 10.1097/pr9.0000000000001123
Abstract: Conditioned pain modulation effects were not different between younger females and males. However, some autonomic activities in women showed significant relationships with conditioned pain modulation. Abstract Introduction: Sex differences in conditioned pain modulation (CPM) have… read more here.
Keywords: pain modulation; modulation effects; sex; conditioned pain ... See more keywords
The effect of expectancy on conditioned pain modulation: evidence from functional near-infrared spectroscopy
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Psychology"
DOI: 10.3389/fpsyg.2025.1525216
Abstract: Background and objective The psychological mechanisms that make Conditioned Pain Modulation (CPM) an effective non-pharmacological intervention are still not fully understood. Expectancy is believed to be a critical psychological factor affecting CPM effects, but its… read more here.
Keywords: spectroscopy; effect; expectancy; conditioned pain ... See more keywords
Exploring the Impact of Affinity and Unpleasantness on Conditioned Pain Modulation among Healthy Individuals
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DOI: 10.3390/biomedicines12061172
Abstract: The variability of the Conditioned Pain Modulation (CPM) effect can be attributed to conditioning stimulus (CS) characteristics, such as intensity, duration, unpleasantness, or affinity. This study investigates the impact of affinity and unpleasantness variables on… read more here.
Keywords: pain modulation; effect; cpm effect; affinity ... See more keywords
Painful Cutaneous Electrical Stimulation vs. Heat Pain as Test Stimuli in Conditioned Pain Modulation †
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DOI: 10.3390/brainsci10100684
Abstract: Different paradigms can assess the effect of conditioned pain modulation (CPM). The aim of the present study was to compare heat pain, as an often used test stimulus (TS), to painful cutaneous electrical stimulation (PCES),… read more here.
Keywords: painful cutaneous; pain modulation; heat pain; heat ... See more keywords
Conditioned Pain Modulation Is Not Impaired in Individuals with Frozen Shoulder: A Case-Control Study
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DOI: 10.3390/ijerph182312330
Abstract: Frozen shoulder (FS) is a poorly understood condition resulting in substantial shoulder pain and mobility deficits. The mechanisms behind FS are not yet fully understood, but, similar to other persistent pain states, central pain mechanisms… read more here.
Keywords: conditioned pain; shoulder; pain; frozen shoulder ... See more keywords