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Vinaxanthone inhibits Semaphorin3A induced axonal growth cone collapse in embryonic neurons but fails to block its growth promoting effects on adult neurons

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-92375-w

Abstract: Semaphorin3A is considered a classical repellent molecule for developing neurons and a potent inhibitor of regeneration after nervous system trauma. Vinaxanthone and other Sema3A inhibitors are currently being tested as possible therapeutics to promote nervous… read more here.

Keywords: adult neurons; cone collapse; sema3a; growth cone ... See more keywords