Identifying novel conopepetides from the venom ducts of Conus litteratus through integrating transcriptomics and proteomics.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2018.09.015
Abstract: The venom ducts of marine cone snails secrete highly complex mixtures of cysteine-rich active peptides, which are generally known as conotoxins or conopeptides and provide a potential fertile resource for pharmacological neuroscience research and the… read more here.
Keywords: novel conopepetides; cone snails; proteomics identifying; identifying novel ... See more keywords
Selecting Potential Neuronal Drug Leads from Conotoxins of Various Venomous Marine Cone Snails in Bali, Indonesia
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.9b03122
Abstract: Many conotoxins, natural peptides of marine cone snails, have been identified to target neurons. Here, we provide data on pharmacological families of the conotoxins of 11 species of cone snails collected in Bali. The identified… read more here.
Keywords: selecting potential; marine cone; potential neuronal; neuronal drug ... See more keywords
Prey Shifts Drive Venom Evolution in Cone Snails
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msae120
Abstract: Abstract Venom systems are complex traits that have independently emerged multiple times in diverse plant and animal phyla. Within each venomous lineage there typically exists interspecific variation in venom composition where several factors have been… read more here.
Keywords: cone snails; prey shifts; venom composition; variation ... See more keywords
Mitogenome Characterization of Four Conus Species and Comparative Analysis
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119411
Abstract: Cone snails, as a type of marine organism, have rich species diversity. Traditionally, classifications of cone snails were based mostly on radula, shell, and anatomical characters. Because of these phenotypic features’ high population variability and… read more here.
Keywords: conus species; four conus; mitogenome characterization; cone snails ... See more keywords
Predatory and Defensive Strategies in Cone Snails
Sign Up to like & getrecommendations! Published in 2024 at "Toxins"
DOI: 10.3390/toxins16020094
Abstract: Cone snails are carnivorous marine animals that prey on fish (piscivorous), worms (vermivorous), or other mollusks (molluscivorous). They produce a complex venom mostly made of disulfide-rich conotoxins and conopeptides in a compartmentalized venom gland. The… read more here.
Keywords: cone snails; defensive strategies; cone snail; predatory defensive ... See more keywords
Cone Snails: A Big Store of Conotoxins for Novel Drug Discovery
Sign Up to like & getrecommendations! Published in 2017 at "Toxins"
DOI: 10.3390/toxins9120397
Abstract: Marine drugs have developed rapidly in recent decades. Cone snails, a group of more than 700 species, have always been one of the focuses for new drug discovery. These venomous snails capture prey using a… read more here.
Keywords: drug; drug discovery; snails big; cone snails ... See more keywords