Confined Migration Drives Stem Cell Differentiation
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DOI: 10.1002/advs.202415407
Abstract: In both endogenous and exogenously‐introduced human mesenchymal stem cells (hMSCs), homing to sites of regeneration requires navigation through complex extracellular matrix environments that impose confinement on migrating cells. Despite its prevalence in vivo, the impact… read more here.
Keywords: differentiation; confined migration; drives stem; migration drives ... See more keywords
High Throughput Confined Migration Microfluidic Device for Drug Screening.
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DOI: 10.1002/smll.202207194
Abstract: Cancer metastasis is the major cause of cancer-related death. Excessive extracellular matrix deposition and increased stiffness are typical features of solid tumors, creating confined spaces for tumor cell migration and metastasis. Confined migration is involved… read more here.
Keywords: drug screening; confined migration; microfluidic device; migration ... See more keywords
Multicompartment cell-based modeling of confined migration: regulation by cell intrinsic and extrinsic factors
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e17-05-0313
Abstract: Though cell and nuclear deformability are expected to influence efficiency of confined migration, their individual and collective influence on migration efficiency remains incompletely understood. In addition to cell intrinsic properties, the relevance of cell extrinsic… read more here.
Keywords: confined migration; cell intrinsic; modeling; migration ... See more keywords