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Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17441
Abstract: The MC4R, a GPCR, has long been a major target for obesity treatment. As the most well‐studied melanocortin receptor subtype, the evolutionary knowledge pushes the drug development and structure–activity relationship (SAR) moving forward. The past…
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Keywords:
basis biological;
mc4r biased;
biased signalling;
conformational basis ... See more keywords