Articles with "conformational basis" as a keyword



MC4R biased signalling and the conformational basis of biological function selections

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Published in 2022 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.17441

Abstract: The MC4R, a GPCR, has long been a major target for obesity treatment. As the most well‐studied melanocortin receptor subtype, the evolutionary knowledge pushes the drug development and structure–activity relationship (SAR) moving forward. The past… read more here.

Keywords: basis biological; mc4r biased; biased signalling; conformational basis ... See more keywords