Conformational Behaviour of Azasugars Based on Mannuronic Acid
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201700080
Abstract: A set of mannuronic‐acid‐based iminosugars, consisting of the C‐5‐carboxylic acid, methyl ester and amide analogues of 1deoxymannorjirimicin (DMJ), was synthesised and their pH‐dependent conformational behaviour was studied. Under acidic conditions the methyl ester and the… read more here.
Keywords: conformational behaviour; acid; acid ester; mannuronic acid ... See more keywords
Exploring the conformational behaviour and aggregation properties of lipid-conjugated AS1411 aptamers.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.06.137
Abstract: AS1411 is a nucleolin-binding aptamer which attracted great interest as active targeting ligand for the selective delivery of therapeutic agents to tumour cells. In this work we selected three AS1411 derivatives 5'-conjugated with lipophilic tails… read more here.
Keywords: as1411; exploring conformational; behaviour; conformational behaviour ... See more keywords