Calmodulin promotes a Ca2+‐dependent conformational change in the C‐terminal regulatory domain of CaV1.2
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14529
Abstract: Calmodulin (CaM) binds to the membrane‐proximal cytosolic C‐terminal domain of CaV1.2 (residues 1520–1669, CT(1520–1669)) and causes Ca2+‐induced conformational changes that promote Ca2+‐dependent channel inactivation (CDI). We report biophysical studies that probe the structural interaction between… read more here.
Keywords: domain cav1; ca2 dependent; 1520 1669; cam ... See more keywords
β‐sheets mediate the conformational change and allosteric signal transmission between the AsLOV2 termini
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.27344
Abstract: Avena sativa phototropin 1 light‐oxygen‐voltage 2 domain (AsLOV2) is a model protein of Per‐Arnt‐Sim (PAS) superfamily, characterized by conformational changes in response to external environmental stimuli. This conformational change begins with the unfolding of the… read more here.
Keywords: conformational change; termini; signal transmission; allosteric signal ... See more keywords
Membrane tension‐dependent conformational change of Isoleucine 106 of loop B diminishes water permeability in FaPIP2;1
Sign Up to like & getrecommendations! Published in 2024 at "Protein Science"
DOI: 10.1002/pro.5204
Abstract: Aquaporins (AQPs) are membrane proteins specialized in facilitating water transport across membranes. Mechanical stress is one of the various stimuli that regulate AQPs. Briefly, there are several studies that report a decrease in permeability upon… read more here.
Keywords: permeability; water; conformational change; membrane tension ... See more keywords
Engineering a calcium-dependent conformational change in Calbindin D9k by secondary elements replacement.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.109065
Abstract: EF-hand is a common motif in Ca2+-binding proteins, some of which present a conformational change upon Ca2+-binding, a relevant property for signal transduction. In the present work, we investigated the behavior of Calbindin D9k, a… read more here.
Keywords: conformational change; calbindin d9k; change; calcium ... See more keywords
Monitoring amyloid-β 42 conformational change using a spray-printed graphene electrode
Sign Up to like & getrecommendations! Published in 2021 at "Electrochemistry Communications"
DOI: 10.1016/j.elecom.2021.106927
Abstract: Abstract Up to now, the reproducibility and stability of graphene-based electrochemical sensors have represented an obstacle to the development of practical biosensing techniques. In this paper we report a cost-effective and highly reproducible graphene-based electrochemical… read more here.
Keywords: change; monitoring amyloid; conformational change; spray printed ... See more keywords
Alkylated pectin: Molecular characterization, conformational change and gel property
Sign Up to like & getrecommendations! Published in 2017 at "Food Hydrocolloids"
DOI: 10.1016/j.foodhyd.2017.03.008
Abstract: Abstract The molecular characterization, conformational change and gel property of alkylated pectins (ALP) prepared by chemical covalent binding with different alkyl chains (C 6 , C 12 , or C 18 ) at different degrees… read more here.
Keywords: molecular characterization; change gel; conformational change; characterization conformational ... See more keywords
pH triggered re‐assembly of nanosphere to nanofiber: The role of peptide conformational change for enhanced cancer therapy
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2017.05.018
Abstract: Abstract pH‐triggered conformational change and subsequent re‐assembly of nanostructures provide a new strategy in nanomedicine for controlled drug release and enhanced therapy. Here, we reported the development of a novel pH‐responsive nano‐assembly as a drug… read more here.
Keywords: peptide conformational; nanosphere nanofiber; conformational change; therapy ... See more keywords
Modeling the conformational change of oil contaminants on Al2O3 surface in aqueous solution: The effect of molecular weight
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2017.05.153
Abstract: Abstract A molecular dynamics simulation study was performed to investigate the influence of molecular weight (MW) on the conformation dynamics of oil contaminants onto Al2O3 surface in aqueous solution. In the present work, two kinds… read more here.
Keywords: al2o3 surface; effect; oil contaminants; conformational change ... See more keywords
Efficient pre-catalytic conformational change of reverse transcriptases from SAMHD1 non-counteracting primate lentiviruses during dNTP incorporation.
Sign Up to like & getrecommendations! Published in 2019 at "Virology"
DOI: 10.1016/j.virol.2019.08.010
Abstract: Unlike HIV-1, HIV-2 and some SIV strains replicate at high dNTP concentrations even in macrophages due to their accessory proteins, Vpx or Vpr, that target SAMHD1 dNTPase for proteasomal degradation. We previously reported that HIV-1… read more here.
Keywords: dntp; reverse; conformational change; samhd1 non ... See more keywords
The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M β-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.7b00176
Abstract: CTX-M β-lactamases provide resistance against the β-lactam antibiotic, cefotaxime, but not a related antibiotic, ceftazidime. β-Lactamases that carry the P167S substitution, however, provide ceftazidime resistance. In this study, CTX-M-14 was used as a model to… read more here.
Keywords: p167s; conformational change; ctx lactamases; ceftazidime ... See more keywords
Gold Nanoflower for Selective Detection of Single Arginine Effect in α-Helix Conformational Change over Lysine in 310-Helix Peptide.
Sign Up to like & getrecommendations! Published in 2019 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.9b00301
Abstract: Hydroxylamine-based growth reaction in the presence of natural l-amino acids (9 mM) and gold nanoparticle seed mostly produce aggregated or nonaggregated gold nanostructures except the cases of immediate precipitation with aspartic acid, glutamic acid, cysteine,… read more here.
Keywords: single arginine; gold nanoflower; arginine; conformational change ... See more keywords