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Published in 2019 at "Molecular Biotechnology"
DOI: 10.1007/s12033-019-00211-4
Abstract: Angiogenesis is a biological process finely tuned by a plethora of pro- and anti-angiogenic molecules, among which vascular endothelial growth factors (VEGFs). Their biological activity is expressed through the interaction with three cognate receptor tyrosine…
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Keywords:
conformational characterization;
characterization recombinant;
vegfr2 domain;
domain ... See more keywords
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Published in 2019 at "PLOS ONE"
DOI: 10.1371/journal.pone.0215442
Abstract: Regulatory agencies establish that a broad physicochemical and biological characterization is necessary for the evaluation of comparability between a biosimilar candidate product and a reference commercial drug. Between them, conformational characterization of proteins is of…
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Keywords:
conformational characterization;
characterization;
candidate;
characterization novel ... See more keywords