PDZ Ligand Binding-Induced Conformational Coupling of the PDZ-SH3-GK Tandems in PSD-95 Family MAGUKs.
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DOI: 10.1016/j.jmb.2017.11.003
Abstract: Discs large (DLG) MAGUKs are abundantly expressed in glutamatergic synapses, crucial for synaptic transmission, and plasticity by anchoring various postsynaptic components including glutamate receptors, downstream scaffold proteins and signaling enzymes. Different DLG members have shared… read more here.
Keywords: pdz; binding induced; conformational coupling; ligand binding ... See more keywords