Pharmacological Chaperones: Beyond Conformational Disorders.
Sign Up to like & getrecommendations! Published in 2018 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2017_68
Abstract: Pharmacological chaperones (PCs) are small molecules that bind to nascent protein targets to facilitate their biogenesis. The ability of PCs to assist in the folding and subsequent forward trafficking of disease-causative protein misfolding mutants has… read more here.
Keywords: conformational disorders; chaperones beyond; disorders pharmacological; beyond conformational ... See more keywords
Emerging role of metabolomics in protein conformational disorders
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Proteomics"
DOI: 10.1080/14789450.2021.1948330
Abstract: ABSTRACT Introduction: Metabolomics focuses on interactions among different metabolites associated with various cellular functions in cells, tissues, and organs. In recent years, metabolomics has emerged as a powerful tool to identify perturbed metabolites, pathways influenced… read more here.
Keywords: conformational disorders; protein conformational; emerging role; disease ... See more keywords